AQUILI Luca    所属   立命館アジア太平洋大学  国際経営学部    職種   准教授
言語種別	英語
発行・発表の年月	2025
形態種別	学術論文
査読	査読あり
標題	Ganoderma lucidum: An Emerging Nutritional Approach to Manage Depression
執筆形態	分担
掲載誌名	FOOD REVIEWS INTERNATIONAL
掲載区分	国外
巻・号・頁	pp.1-22
著者・共著者	Jin Hongkai, Aquili Luca, Heng Boon Chin, Strekalova Tatyana, Fung Man-Lung, Tipoe George Lim, Kocabicak Ersoy, Blokland Arjan, Temel Yasin, Lu Zhiliang, Kalueff Allan, Wong Kah Hui, Lim Lee Wei
概要	This review evaluates Ganoderma lucidum, a medicinal mushroom, as a nutritional approach to depression. Its polysaccharides, triterpenoids, and other bioactive compounds show antidepressant-like effects in preclinical models through monoamine regulation, brain-derived neurotrophic factor signaling, antioxidant activity, and suppression of inflammatory cytokines. Limited human evidence suggests possible symptom improvement, but clinical data remain sparse and formulations vary considerably. The article presents G. lucidum as a potential complementary strategy rather than an established treatment and calls for standardized preparations, dose studies, safety assessment, and rigorous randomized clinical trials.
DOI	10.1080/87559129.2025.2466456
ISSN	8755-9129