AQUILI Luca    所属   立命館アジア太平洋大学  国際経営学部    職種   准教授
言語種別	英語
発行・発表の年月	2021
形態種別	学術論文
査読	査読あり
標題	GABA Supplementation Negatively Affects Cognitive Flexibility Independent of Tyrosine
執筆形態	コレスポンディング
掲載誌名	JOURNAL OF CLINICAL MEDICINE
掲載区分	国外
巻・号・頁	10(9)
国際共著	国際共著
著者・共著者	Lim Lee Wei, Aquili Luca
概要	This double-blind study tested GABA and tyrosine supplementation, separately and together, in 48 healthy adults completing a task-switching measure of cognitive flexibility. Participants receiving GABA alone or GABA plus tyrosine performed worse than placebo, whereas tyrosine alone produced no reliable improvement. Tyrosine did not offset the negative effect of GABA, providing no evidence of an interaction between the supplements. The findings suggest that acute oral GABA can impair flexible control independently of tyrosine and caution against assuming that over-the-counter neurotransmitter precursors or supplements necessarily enhance executive performance.
DOI	10.3390/jcm10091807
ISSN	2077-0383