AQUILI Luca
   所属   立命館アジア太平洋大学  国際経営学部
   職種   准教授
言語種別 英語
発行・発表の年月 2020
形態種別 学術論文
査読 査読あり
標題 Occasion setters determine responses of putative DA neurons to discriminative stimuli
執筆形態 筆頭著者
掲載誌名 NEUROBIOLOGY OF LEARNING AND MEMORY
掲載区分国外
巻・号・頁 173
国際共著 国際共著
著者・共著者 Aquili Luca, Bowman Eric M., Schmidt Robert
概要 This electrophysiological study recorded putative ventral tegmental dopamine neurons while rats used occasion setters to interpret discriminative cues. At the population level, neurons did not respond uniformly to the occasion-setting cue. Individual units instead showed heterogeneous increases, decreases, or no change, and responses to discriminative stimuli were likewise more diverse than the population average suggested. The results indicate that dopamine activity reflects contextual control through locally differentiated signals rather than a single homogeneous value code. They also caution against inferring uniform neuronal functions from population-level averages alone.
DOI 10.1016/j.nlm.2020.107270
ISSN 1074-7427