AQUILI Luca
   所属   立命館アジア太平洋大学  国際経営学部
   職種   准教授
言語種別 英語
発行・発表の年月 2020
形態種別 学術論文
査読 査読あり
標題 Behavioural responses of anxiety in aversive and non-aversive conditions between young and aged Sprague-Dawley rats
執筆形態 分担
掲載誌名 BEHAVIOURAL BRAIN RESEARCH
掲載区分国外
巻・号・頁 385
国際共著 国際共著
著者・共著者 Hiew Lih Fhung, Khairuddin Sharafuddin, Aquili Luca, Koh Junhao, Fung Man-Lung, Lim Wei Ling, Lim Lee Wei
概要 This study compared anxiety-related behavior in young and aged Sprague–Dawley rats under aversive and less aversive testing conditions. Animals completed the home-cage emergence and elevated-plus-maze tests under bright or dim illumination. Young rats emerged sooner and explored more, whereas bright light increased anxiety-related behavior in both age groups. Age also interacted with illumination differently across measures, indicating that the tasks capture partly distinct components of anxiety and exploration. The results show that age and environmental aversiveness must both be considered when interpreting rodent anxiety tests.
DOI 10.1016/j.bbr.2020.112559
ISSN 0166-4328