AQUILI Luca    所属   立命館アジア太平洋大学  国際経営学部    職種   准教授
言語種別	英語
発行・発表の年月	2020
形態種別	学術論文
査読	査読あり
標題	Dopamine depletion effects on cognitive flexibility as modulated by tDCS of the dlPFC
執筆形態	コレスポンディング
掲載誌名	BRAIN STIMULATION
掲載区分	国外
巻・号・頁	13(1),pp.105-108
国際共著	国際共著
著者・共著者	Borwick Ciara, Lal Reece, Lim Lee Wei, Stagg Charlotte J., Aquili Luca
概要	This double-blind, sham-controlled study tested whether depleting catecholamine precursors changes the cognitive effects of anodal stimulation over the dorsolateral prefrontal cortex. Stimulation reduced perseverative errors in task switching, whereas precursor depletion slowed responses; neither manipulation reliably affected reversal learning. Combining depletion with stimulation produced performance that did not differ from control. The pattern indicates that prefrontal transcranial direct-current stimulation and reduced dopamine availability influence selected components of flexibility, with their combined effects depending on baseline dopaminergic tone rather than producing a simple additive impairment or benefit.
DOI	10.1016/j.brs.2019.08.016
ISSN	1935-861X