OKUYAMA Ryo
   Department   Ritsumeikan Asia Pacific University  College of International Management
   Position   Professor
Language English
Publication Date 2023/05
Type Research paper
Peer Review Peer reviewed
Title Strengthening the Competitiveness of Japan’s Pharmaceutical Industry: Analysis of Country Differences in the Origin of New Drugs and Japan’s Highly Productive Firm.
Contribution Type Single Work
Journal Biological and Pharmaceutical Bulletin
Journal TypeAnother Country
Publisher The Pharmaceutical Society of Japan
Volume, Issue, Page 46(5),pp.718-724
Total page number 7
Authorship Lead author,Corresponding author
Author and coauthor Ryo Okuyama
Details The author found that bio-ventures established in the 1990s and 2000s played a crucial role in creating new drugs approved by the FDA from 2017 to 2022 in regions outside of Japan. In contrast, in Japan, all approved drugs were created by old incumbent pharmaceutical companies, highlighting the urgent need to foster drug discovery start-ups in Japan. A case study of the Japanese company that created the largest number of FDA-approved drugs suggests that focused investment in modality technology development, strengthening collaboration with academia in biology, and the reutilizing small-molecule drug discovery capabilities are essential for improving drug discovery productivity.
DOI https://doi.org/10.1248/bpb.b23-00107