Department   Ritsumeikan Asia Pacific University  College of International Management
   Position   Professor
Language English
Publication Date 2023/11
Type Research paper
Peer Review Peer reviewed
Title mRNA and Adenoviral Vector Vaccine Platforms Utilized in COVID-19 Vaccines: Technologies, Ecosystem, and Future Directions.
Contribution Type Single Work
Journal Vaccines
Journal TypeAnother Country
Volume, Issue, Page 11(12),pp.1737
Total page number 24
Authorship Lead author,Corresponding author
Author and coauthor Okuyama R
Details New technological platforms, such as mRNA and adenoviral vector vaccines, have been utilized to develop coronavirus disease 2019 (COVID-19) vaccines. These new modalities enable rapid and flexible vaccine design and cost-effective and swift manufacturing, effectively combating pandemics caused by mutating viruses. Innovation ecosystems, including universities, startups, investors, and governments are crucial for developing these cutting-edge technologies. This review summarizes the research and development trajectory of these vaccine technologies, their investments, and the support surrounding them, in addition to the technological details of each technology. In addition, this study examines the importance of an innovation ecosystem in developing novel technologies, comparing it with the case of Japan, which has lagged behind in COVID-19 vaccine development. It also explores the direction of vaccine development in the post-COVID-19 era.
DOI https://doi.org/10.3390/vaccines11121737