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1.
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2024/03
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論文
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Trends in COVID-19 Vaccine Development: Vaccine Platform, Developer, and Nationality. Vaccines 12(3),pp.259 （単著）
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2.
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2024/02
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論文
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Increased contribution of small companies to late-entry drugs: a changing trend in FDA-approved drugs during the 2020s. Drug Discovery Today 29(2),pp.103866 （単著）
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3.
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2023/12
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論文
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Academia’s contribution to drug discovery: current status and perspectives in Japan. Translational and Regulatory Sciences 5(3),pp.57-64 （単著）
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4.
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2023/11
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論文
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mRNA and Adenoviral Vector Vaccine Platforms Utilized in COVID-19 Vaccines: Technologies, Ecosystem, and Future Directions. Vaccines 11(12),pp.1737 （単著）
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5.
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2023/09
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論文
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アカデミアの創薬への貢献：日本の現状と展望 Translational and Regulatory Sciences(日本語翻訳版) （単著）
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6.
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2023/07
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論文
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Advancements in Drug Repurposing: Examples in Psychiatric Medications. International Journal of Molecular Sciences 24(13),pp.11000 （単著）
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7.
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2023/06
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論文
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Chronological Analysis of First-in-Class Drugs Approved from 2011 to 2022: Their Technological Trend and Origin. Pharmaceutics 15(7),pp.1794 （単著）
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8.
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2023/05
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論文
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Strengthening the Competitiveness of Japan’s Pharmaceutical Industry: Analysis of Country Differences in the Origin of New Drugs and Japan’s Highly Productive Firm. Biological and Pharmaceutical Bulletin 46(5),pp.718-724 （単著）
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9.
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2023/04
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論文
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Modality diversification and best-in-class small-molecule drugs: Recent trend of orphan drug development. Medicine in Drug Discovery 18,pp.100156 （単著）
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10.
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2022/12
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論文
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Nurturing Deep Tech to Solve Social Problems: Learning from COVID-19 mRNA Vaccine Development. Pathogens 11(12),pp.1469 （単著）
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11.
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2020/10
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著書
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サイエンス･ベースド･イノベーション－ディープテックのマネジメント－ （単著）
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12.
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2020/06
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論文
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Importance of drug target selection capability for new drug innovation: definition, fostering process and interaction with organizational management. Prometheus 36(2),pp.135-152 （共著）
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13.
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2020/03
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論文
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創薬における「創薬標的選定能力」―革新的新薬創製の競争優位に寄与する新しい能力概念とその成因― イノベーション・マネジメント 17,141-156頁 （共著）
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14.
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2019/10
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論文
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激変する新薬開発の最前線 主戦場はバイオベンチャーへ 医療白書2019年度版 30-35頁 （単著）
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15.
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2019/09
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論文
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企業側からみたスター・サイエンティストとの協働と可能性：医薬品産業のケース 研究技術計画 34(2),129-138頁 （単著）
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16.
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2017/09
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論文
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アカデミア創薬の課題－創薬応用研究部分の能力に関する分析－ 医療と社会 27(2),237-250頁 （共著）
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17.
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2017/06
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論文
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アカデミア創薬の背景と現状 -産学官各々の立場からの分析- 産学連携学 13(2),127-134頁 （共著）
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18.
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2017/02
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論文
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Importance of tacit knowledge in incremental innovation: Implications from drug discovery cases Journal of Strategy and Management 10(1),pp.118-130 （単著）
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19.
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2015/12
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論文
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The types of scientific information and technologies acquired from university-industry relationships in the Japanese pharmaceutical industry - An empirical study from 1980 to 2012 International Journal of Technology Transfer and Commercialisation 13(3/4),pp.178-191 （単著）
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20.
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2014/07
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論文
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Acquisition of drug candidates in New Drug Development in Japan Proceedings of Portland International Center for Management of Engineering and Technology （共著）
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21.
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2013/07
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論文
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University-Industry Collaboration in Drug Discovery in Japan: An Empirical Analysis over Thirty Years Proceedings of Portland International Center for Management of Engineering and Technology （共著）
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22.
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2013/06
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論文
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Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 Diabetes ACS Med Chem Lett. 4(8),pp.790-794 （共著）
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23.
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2013/05
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論文
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Aminopyrazole–Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies ACS Med. Chem. Lett. 4(9),pp.829-834 （共著）
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24.
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2012/10
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論文
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Phenylalanine Derivatives as GPR142 Agonists for the Treatment of Type II Diabetes Bioorg Med Chem Lett. 22(19),pp.6218-6223 （共著）
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25.
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2012/07
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論文
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Discovery and optimization of a novel series of GPR142 agonists for the treatment of type 2 diabetes mellitus Bioorg Med Chem Lett. 22(18),pp.5942-5947 （共著）
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26.
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2011/01
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論文
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Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor γ Ligand, Cerco-A. Biol Pharm Bull. 34(7),pp.1094-1104 （共著）
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27.
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2009/10
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論文
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Novel benzoylpiperidine-based stearoyl-CoA desaturase-1 inhibitors: Identification of 6-[4-(2-methylbenzoyl)piperidin-1-yl]pyridazine-3-carboxylic acid (2-hydroxy-2- pyridin-3-ylethyl)amide and its plasma triglyceride-lowering effects in Zucker fatty rats. Bioorg Med Chem Lett. 20(1),pp.341-345 （共著）
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28.
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2009/08
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論文
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Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part I: Discovery of 3-(2-hydroxyethoxy)-4-methoxy-N-[5-(3-trifluoromethylbenzyl)thiazol -2-yl]benzamide Bioorg Med Chem Lett. 19(15),pp.4151-4158 （共著）
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29.
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2009/08
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論文
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Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl) thiazol-2-yl]benzamide and its biological evaluation Bioorg Med Chem Lett. 19(15),pp.4159-4166 （共著）
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30.
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2007/01
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論文
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In vivo antisense activity of ENA oligonucleotides targeting PTP1B mRNA in comparison of that of 2'-MOE-modified oligonucleotides Nucleic Acids Symp Ser (Oxf). 51,pp.111-112 （共著）
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31.
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2006/09
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論文
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Direct comparison of in vivo antisense activity of ENAregistered oligonucleotides targeting PTP1B mRNA with that of 2'-MOE-modified oligonucleotides Oligonucleotides 16,pp.253-262 （共著）
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32.
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2005/06
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論文
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Turnover and Characterization of UDP-N-Acetylglucosaminyl Transferase (OGT) in a Stably Transfected HeLa Cell Line Biochem. Biophys. Res. Commun. 332(1),pp.263-270 （共著）
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33.
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2005/04
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論文
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Glucosamine Induces Rapid Desensitization of Glucose Transport in Isolated Adipocytes by Increasing GlcN-6-P Levels Biochem. Biophys. Res. Commun. 329(3),pp.1155-1161 （共著）
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34.
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2005/04
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論文
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Identification of molecular target of AMP-activated protein kinase activator by affinity purification and mass spectrometry Anal. Chem. 77(7),pp.2050-2055 （共著）
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35.
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2004/08
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論文
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Potential Regulation of Nuclear UDP-N-acetylglucosaminyl Transferase (OGT) by Substrate Availability : Ability of Chromatin Protein to Bind UDP-N-acetylglucosamine and Reduce OGT-mediated O-linked Glycosylation Biol. Pham. Bull. 27(8),pp.1293-1296 （共著）
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36.
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2004/06
|
論文
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Differential Effects of Vanadate on UDP-N-Acetylglucosaminyl Transferase (OGT) Activity Derived from Cytosol and Nucleosol Biochem. Biophys. Res. Commun. 318(4),pp.911-915 （共著）
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37.
|
2003/09
|
論文
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UDP-N-acetylglucosaminyl Transferase (OGT) in Brain Tissue: Temperature Sensitivity and Subcellular Distribution of Cytosolic and Nuclear Enzyme J. Neurochem. 86(5),pp.1271-1280 （共著）
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38.
|
2003/06
|
論文
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High Glucose Potentiates Palmitate-induced NO-mediated Cytotoxicity through Generation of Superoxide in Clonal Beta-cell HIT-T15 FEBS Lett. 545(2-3),pp.219-223 （共著）
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39.
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2003/03
|
論文
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Measurement of UDP-N-Acetylglucosaminyl Transferase (OGT) in Brain Cytosol and Characterization of Anti-OGT Antibodies Anal. Biochem. 314(2),pp.169-179 （共著）
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40.
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2001/09
|
論文
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Cytosolic O-GlcNAc Accumulation is not Involved in Beta-cell Death in HIT-T15 or Min6 Biochem. Biophys. Res. Commun. 287(2),pp.366-371 （共著）
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41.
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1994/10
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論文
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Differential Potentiation by Depolarization of the Effects of Calcium Antagonists on Contraction and Ca2+ Current in Guinea-pig Heart Br. J. Pharmacol. 113(2),pp.451-456 （共著）
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42.
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1993/02
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論文
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Quaternary Diltiazem Can Act from Both Sides of the Membrane in Ventricular Myocytes Jpn. J. Pharmacol. 61(3),pp.263-266 （共著）
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